8-Hydroxy Quinaldine

8-Hydroxy Quinaldine

SCHEMBL3265166

Cc1ccc2cccc(O)c2n1.Cc1ccc2cccc(O)c2n1.Oc1ccccc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 2/20 0.82
KMT2A Q03164 5/20 0.50
KDM4E B2RXH2 3/20 0.50
PLAU P00749 1/20 0.50
NCF1 P14598 1/20 0.50
ALOX12 P18054 2/20 0.49
ALDH1A1 P00352 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
HPGD P15428 1/20 0.49
CYP2C19 P33261 1/20 0.49
HIF1A Q16665 1/20 0.49
HSD17B10 Q99714 1/20 0.49
RAB9A P51151 2/20 0.48
CCR1 P32246 1/20 0.48
CCR5 P51681 1/20 0.48
CD74 P04233 1/20 0.47
MIF P14174 1/20 0.47
PARP1 P09874 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-Hydroxy Quinaldine SCHEMBL625310 0.98 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL19327239 0.98 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL19640292 0.98 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL8634752 0.98 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL30128554 0.98 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL4386958 0.98 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL4169321 0.92 METAP2 (0.70) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL29483489 0.91 METAP2 (1.00) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL297247 0.91 METAP2 (1.00) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL195825 0.90 METAP2 (0.72) METAP2KMT2AKDM4EPLAUNCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1000999-B1 COMPOUNDS FOR ORGANIC EL DEVICES AND ORGANIC EL DEVICES TDK CORP (JP) 2010-02-24 EP disclosed
CN-101003545-A Method for preparing hydroxylquinoline aluminium of blue green type mixing ligand TAIYUAN TECH UNIV (CN) 2007-07-25 CN disclosed
US-6797414-B2 LITHIUM OXIDE INTERFACES; CONCENTRATION GRADIENTS; CONCURRENT EVAPORATION; LOW VOLTAGE DRIVES; EFFICIENCY SAMSUNG SDI CO., LTD. (KR) 2004-09-28 US disclosed
US-20020187367-A1 Organic EL device and method of manufacturing organic EL device NEC CORPORATION 2002-12-12 US disclosed