8-Hydroxy Quinaldine

8-Hydroxy Quinaldine

SCHEMBL4386958

Cc1ccc2cccc(O)c2n1.Cc1ccc2cccc(O)c2n1.Oc1ccccc1.[Ga]

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 2/20 0.79
KMT2A Q03164 5/20 0.49
KDM4E B2RXH2 3/20 0.49
PLAU P00749 1/20 0.49
NCF1 P14598 1/20 0.49
ALOX12 P18054 2/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
CYP2C19 P33261 1/20 0.47
HIF1A Q16665 1/20 0.47
HSD17B10 Q99714 1/20 0.47
RAB9A P51151 2/20 0.47
CCR1 P32246 1/20 0.47
CCR5 P51681 1/20 0.47
CD74 P04233 1/20 0.46
MIF P14174 1/20 0.46
PARP1 P09874 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-Hydroxy Quinaldine SCHEMBL3265166 0.98 METAP2 (0.82) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL19640292 0.97 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL30128554 0.97 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL625310 0.97 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL8634752 0.97 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL19327239 0.97 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL29885026 0.91 METAP2 (0.96) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL4401768 0.91 METAP2 (0.96) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL4169321 0.91 METAP2 (0.70) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL461474 0.91 METAP2 (0.70) METAP2KMT2AKDM4EPLAUNCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT TOYO INK MFG. CO., LTD. (JP) 2009-06-18 US disclosed
EP-2025733-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ORGANIC ELECTROLUMINESCENCE ELEMENT TOYO INK MFG. CO., LTD. (JP) 2009-02-18 EP disclosed
US-6703146-B1 ELECTRON INJECTION OR ELECTRON TRANSPORTING LAYER HAS AN IONIZATION POTENTIAL HIGHER THAN THAT OF THE LUMINESCENT LAYER NEC CORPORATION (JP) 2004-03-09 US disclosed
US-6660411-B2 Can emit light at a low voltage and a high efficiency and can be driven in a stable manner MITSUBISHI CHEMICAL CORPORATION (JP) 2003-12-09 US disclosed
US-20020055015-A1 Organic electroluminescent device MITSUBISHI CHEMICAL CORPORATION (JP) 2002-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156827-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS AND ORGANIC ELECTROLUMINESCENT ELEMENT ELP1, ELAVL1, ELF3 METAP2 3425/4885KMT2A 905/4885KDM4E 1648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.