SCHEMBL30128591

SCHEMBL30128591

O=C(O)C1(CCc2ccccc2)C=CC=CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.41
KEAP1 Q14145 1/20 0.38
HDAC2 Q92769 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HDAC3 O15379 1/20 0.36
MAPK1 P28482 1/20 0.36
ADRA1A P35348 1/20 0.36
HDAC4 P56524 1/20 0.36
SLC6A3 Q01959 1/20 0.36
HDAC1 Q13547 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
FFAR1 O14842 1/20 0.36
EPHX1 P07099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28616886 0.87 ALDH1A1 (0.36) HSD11B1ALDH1A1SMN1; SMN2TDP1MAPT
SCHEMBL13519462 0.84 HSD11B1 (0.37) HSD11B1KEAP1HDAC2HDAC8HDAC6
SCHEMBL20377192 0.84 HSD11B1 (0.39) HSD11B1KEAP1HDAC2HDAC6ALDH1A1
SCHEMBL29034434 0.82 EPHX2 (0.35) HSD11B1ALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL29028274 0.76 CA12 (0.33) HSD11B1HDAC2HDAC8HDAC6ALDH1A1
SCHEMBL27583423 0.76 KDM1A (0.39) HSD11B1KEAP1ALDH1A1TDP1GAA
SCHEMBL6667419 0.75 HSD11B1 (0.37) HSD11B1ALDH1A1TDP1MAPTMEN1
SCHEMBL3874789 0.75
Isopropylbenzene SCHEMBL30175415 0.73 OPRM1 (0.37) ALDH1A1SMN1; SMN2EPHX1NPC1RAB9A
SCHEMBL17965483 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108341901-B Catalyst component for ethylene polymerization, preparation method thereof and catalyst for ethylene polymerization 中国石油化工股份有限公司 2022-12-13 CN disclosed