SCHEMBL30128828

SCHEMBL30128828

N#Cc1ccc(B(O)O)cc1OC(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 3/20 0.39
KCNJ1 P48048 1/20 0.37
KCNH2 Q12809 1/20 0.37
SLC22A12 Q96S37 3/20 0.36
IDH1 O75874 1/20 0.35
MGLL Q99685 2/20 0.35
ABL1 P00519 1/20 0.34
AR P10275 5/20 0.34
BCAT2 O15382 1/20 0.33
BCAT1 P54687 1/20 0.33
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22228582 1.00 ENPP2 (0.39) ENPP2KCNJ1KCNH2SLC22A12IDH1
SCHEMBL20659355 0.90 ENPP2 (0.39) ENPP2SLC22A12MGLLABL1AR
SCHEMBL29951886 0.78 AR (0.49) ENPP2AR
SCHEMBL249673 0.78 AR (0.49) ENPP2AR
SCHEMBL3020739 0.78 AR (0.46) KCNJ1KCNH2SLC22A12IDH1AR
SCHEMBL22683815 0.76 APP (0.45) ENPP2KCNH2MGLLABL1
SCHEMBL31437950 0.76 MGLL (0.39) ENPP2MGLLABL1
SCHEMBL1496432 0.76 MGLL (0.39) ENPP2MGLLABL1
SCHEMBL29952898 0.76 APP (0.45) ENPP2KCNH2MGLLABL1
SCHEMBL28947751 0.76 AR (0.47) KCNJ1KCNH2SLC22A12IDH1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111094239-B Novel compound and organic light emitting device comprising the same 株式会社LG化学 2022-12-13 CN disclosed