Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 8/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | BRS3 | P32247 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729718 | 0.88 | MCL1 (0.58) | LTB4R2MCL1 | |
| SCHEMBL10902221 | 0.87 | LTB4R2 (0.60) | LTB4R2MCL1PPARGBRS3AGTR1 | |
| SCHEMBL3230323 | 0.86 | LTB4R2 (0.63) | LTB4R2PPARGBRS3AGTR1 | |
| SCHEMBL225203 | 0.83 | HNF4A (0.71) | HNF4A | |
| SCHEMBL25146615 | 0.82 | MCL1 (0.52) | LTB4R2MCL1PPARGBRS3AGTR1 | |
| SCHEMBL7722704 | 0.82 | MCL1 (0.52) | LTB4R2MCL1PPARGBRS3AGTR1 | |
| SCHEMBL7731090 | 0.79 | MCL1 (0.49) | LTB4R2MCL1PPARGBRS3AGTR1 | |
| SCHEMBL3906504 | 0.78 | BRS3 (0.70) | LTB4R2BRS3AGTR1 | |
| SCHEMBL29993202 | 0.78 | HSD11B1 (0.47) | MCL1 | |
| SCHEMBL7388817 | 0.78 | PTPN11 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3367143-B1 | POLARIZING PHOTOCHROMIC DEVICES AND METHODS OF MAKING THE SAME | TRANSITIONS OPTICAL INC (US) | 2023-01-11 | — | — | EP | claimed |