Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | BRS3 | P32247 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29760459 | 0.85 | HNF4A (0.52) | LTB4R2 | |
| SCHEMBL3230323 | 0.82 | LTB4R2 (0.63) | LTB4R2PPARGBRS3AGTR1 | |
| SCHEMBL25146615 | 0.81 | MCL1 (0.52) | MCL1LTB4R2PPARGBRS3AGTR1 | |
| SCHEMBL7722704 | 0.81 | MCL1 (0.52) | MCL1LTB4R2PPARGBRS3AGTR1 | |
| SCHEMBL5268526 | 0.80 | HNF4A (0.59) | — | |
| SCHEMBL10902221 | 0.80 | LTB4R2 (0.60) | MCL1LTB4R2PPARGBRS3AGTR1 | |
| SCHEMBL30129062 | 0.79 | HNF4A (0.51) | MCL1LTB4R2PPARGBRS3AGTR1 | |
| SCHEMBL7729718 | 0.77 | MCL1 (0.58) | MCL1LTB4R2 | |
| SCHEMBL28225124 | 0.76 | FOLH1 (0.46) | MCL1PPARG | |
| SCHEMBL7731088 | 0.75 | MCL1 (0.52) | MCL1LTB4R2PPARGBRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-5858270-A | Difluorooxymethane derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |