Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | RET | P07949 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23883581 | 1.00 | RXRA (0.39) | RXRARXRBRXRGRETGRIN1 | |
| SCHEMBL30129621 | 0.80 | RXRB (0.38) | RXRARXRBRXRGL3MBTL1KDM4E | |
| SCHEMBL23883586 | 0.80 | RXRB (0.38) | RXRARXRBRXRGL3MBTL1KDM4E | |
| SCHEMBL30165645 | 0.79 | RXRA (0.37) | RXRARXRBRXRGRETGRIN1 | |
| SCHEMBL30129616 | 0.79 | L3MBTL1 (0.40) | RXRARXRBRXRGGRIN1GRIN2B | |
| SCHEMBL23883588 | 0.77 | NPC1 (0.43) | L3MBTL1KDM4E | |
| SCHEMBL30129535 | 0.77 | NPC1 (0.43) | L3MBTL1KDM4E | |
| SCHEMBL30129682 | 0.77 | ICMT (0.35) | RXRARXRBRXRGGRIN1GRIN2B | |
| SCHEMBL23883167 | 0.77 | KCNK3 (0.46) | RXFP1CYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL23903819 | 0.72 | KMT2A (0.37) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115485312-B | Sterically hindered phosphino-urea supported nickel (II) or palladium (II) catalysts for the copolymerization of ethylene and polar comonomers | 陶氏环球技术有限责任公司 | 2024-11-19 | — | — | CN | disclosed |
| EP-4126991-A1 | STERICALLY HINDERED PHOSPHINO-UREA SUPPORTED NICKEL(II) OR PALLADIUM(II) CATALYSTS FOR THE COPOLYMERIZATION OF ETHYLENE AND POLAR COMONOMERS | Dow Global Technologies LLC (US) | 2023-02-08 | — | — | EP | disclosed |
| CN-115485312-A | Sterically hindered phosphino-urea supported nickel (II) or palladium (II) catalysts for copolymerization of ethylene and polar comonomers | 陶氏环球技术有限责任公司 | 2022-12-16 | — | — | CN | disclosed |