Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NQO1 | P15559 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16863152 | 0.77 | KDM4E (0.53) | ALDH1A1KDM4EGAACYP2C9CYP3A4 | |
| SCHEMBL15542047 | 0.77 | KDM4E (0.49) | ALDH1A1KDM4EGAACYP2C9CYP3A4 | |
| SCHEMBL15541690 | 0.74 | KDM4E (0.53) | ALDH1A1KDM4ECYP2C9CYP3A4SMN1; SMN2 | |
| SCHEMBL29950209 | 0.74 | KDM4E (0.53) | ALDH1A1KDM4ECYP2C9CYP3A4SMN1; SMN2 | |
| SCHEMBL27503546 | 0.66 | SMN1; SMN2 (0.39) | ALDH1A1KDM4ECYP2C9SMN1; SMN2MAPT | |
| SCHEMBL29076941 | 0.66 | KMT2A (0.55) | ALDH1A1KDM4EGAACYP2C9CYP3A4 | |
| SCHEMBL14417276 | 0.64 | NQO1 (0.51) | ALDH1A1KDM4ECYP2C9CYP3A4SMN1; SMN2 | |
| SCHEMBL304367 | 0.63 | KMT2A (0.62) | ALDH1A1KDM4EGAACYP2C9CYP3A4 | |
| SCHEMBL29709713 | 0.63 | KMT2A (0.62) | ALDH1A1KDM4EGAACYP2C9CYP3A4 | |
| SCHEMBL29416517 | 0.63 | KMT2A (0.62) | ALDH1A1KDM4EGAACYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240293443-A1 | HEPARAN SULFATE MIMETICS TO IMPROVE GLUCOSE CLEARANCE | GORDTS PHILIP L S M (US) | 2024-09-05 | — | — | US | claimed |
| WO-2022261480-A1 | HEPARAN SULFATE MIMETICS TO IMPROVE GLUCOSE CLEARANCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-15 | — | — | WO | claimed |
| US-20240293443-A1 | HEPARAN SULFATE MIMETICS TO IMPROVE GLUCOSE CLEARANCE | GORDTS PHILIP L S M (US) | 2024-09-05 | — | — | US | disclosed |
| WO-2022261480-A1 | HEPARAN SULFATE MIMETICS TO IMPROVE GLUCOSE CLEARANCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240293443-A1 | HEPARAN SULFATE MIMETICS TO IMPROVE GLUCOSE CLEARANCE | FABP4, APMAP, SLC2A4 | ALDH1A1 3423/4885KDM4E 3334/4885GAA 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.