SCHEMBL304367

SCHEMBL304367

O=c1oc2ccccc2c2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.62
NPSR1 Q6W5P4 4/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
RXFP1 Q9HBX9 3/20 0.62
MAPK1 P28482 2/20 0.62
NPC1 O15118 1/20 0.62
RAB9A P51151 1/20 0.62
ALDH1A1 P00352 7/20 0.59
KDM4E B2RXH2 4/20 0.59
GAA P10253 1/20 0.59
MAPT P10636 4/20 0.58
CYP3A4 P08684 2/20 0.58
GLA P06280 2/20 0.58
HSD17B10 Q99714 2/20 0.58
HPGD P15428 1/20 0.58
PGAM1 P18669 1/20 0.58
MAOA P21397 1/20 0.58
CASP1 P29466 1/20 0.58
CASP7 P55210 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29709713 1.00 KMT2A (0.62) KMT2ANPSR1SMN1; SMN2RXFP1MAPK1
SCHEMBL29416517 1.00 KMT2A (0.62) KMT2ANPSR1SMN1; SMN2RXFP1MAPK1
Water SCHEMBL28602073 0.98 KMT2A (0.60) KMT2ANPSR1SMN1; SMN2RXFP1MAPK1
SCHEMBL10025819 0.86 L3MBTL1 (0.69) KMT2ANPSR1SMN1; SMN2RXFP1MAPK1
SCHEMBL9787769 0.86 MAOA (0.74) KMT2ASMN1; SMN2MAPK1NPC1RAB9A
SCHEMBL16802258 0.84 SMN1; SMN2 (0.62) KMT2ANPSR1SMN1; SMN2RXFP1MAPK1
SCHEMBL30966887 0.84 ALDH1A1 (0.58) KMT2ANPSR1SMN1; SMN2RXFP1MAPK1
SCHEMBL29391754 0.84 ALDH1A1 (0.58) KMT2ANPSR1SMN1; SMN2RXFP1MAPK1
SCHEMBL257 0.84 ALDH1A1 (0.58) KMT2ANPSR1SMN1; SMN2RXFP1MAPK1
SCHEMBL10025828 0.83 L3MBTL1 (0.60) KMT2ANPSR1SMN1; SMN2RXFP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250276994-A1 CAP ANALOG FOR THE 5'-END OF EUKARYOTIC MESSENGER RNAS WESTFÄLISCHE WILHELMS-UNIVERSITÄT (DE) 2025-09-04 US claimed
US-12227613-B2 Photo-patternable organic semiconductor (OSC) polymers and methods of formation and applications thereof CORNING INCORPORATED (US) 2025-02-18 US claimed
CN-119119070-A Organic compound with dibenzopyranone-like ring as core, preparation method and application thereof, and application of organic electroluminescent device 烟台先进材料与绿色制造山东省实验室 2024-12-13 CN claimed
US-20240400503-A1 NOVEL PHOTOINITIATORS IGM RESINS ITALIA S.R.L. (IT) 2024-12-05 US claimed
EP-4412990-A1 NOVEL PHOTOINITIATORS IGM Resins Italia S.r.l. (IT) 2024-08-14 EP claimed
CN-118475556-A Novel photoinitiators 意大利艾坚蒙树脂有限公司 2024-08-09 CN claimed
CN-118420837-A Decrosslinking modified elastomer regenerated material, and regeneration method and application thereof 中山旺材科技有限公司 2024-08-02 CN claimed
CN-116178332-B N-substituted benzocoumarin compound with breast cancer resisting activity and preparation method and application thereof 新乡医学院 2024-05-24 CN claimed
EP-4367127-A1 CAP ANALOG FOR THE 5'-END OF EUKARYOTIC MESSENGER RNAS Westfälische Wilhelms-Universität Münster (DE) 2024-05-15 EP claimed
CN-117865925-A 3, 4-benzocoumarin compound based on complex functional aromatic hydrocarbon and preparation method and application thereof 上海瑞苷生物科技有限公司 2024-04-12 CN claimed
EP-0710225-A1 FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES PROGEN Biotechnik GmbH (DE) 1996-05-08 EP claimed
WO-1995032181-A1 FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES PROGEN BIOTECHNIK GMBH (DE) 1995-11-30 WO claimed
US-5216146-A 2-benzocoumarinyl-carbapenems MERCK & CO., INC. (US) 1993-06-01 US claimed
US-5182384-A Chemical intermediates for bactericides MERCK & CO., INC. (US) 1993-01-26 US claimed
EP-0515232-A1 2-benzocoumarinyl-carbapenems MERCK & CO. INC. (US) 1992-11-25 EP claimed
EP-0515217-A1 2-Benzocoumarinyl carbapenems MERCK & CO. INC. (US) 1992-11-25 EP claimed
US-5162314-A 2-benzocoumarinyl carbapenems MERCK & CO., INC. (US) 1992-11-10 US claimed
US-5104894-A Ellagic acid analogues UNIVERSITY OF GUELPH (CA) 1992-04-14 US claimed
US-5073295-A Coated with block copolymer of ethylene oxide and propylene oxide, ethoxylated stearyldiphenyloxyethyl diethylenetriamine; wear resistant, free-flowing, dustless CIBA-GEIGY CORPORATION (US) 1991-12-17 US claimed
US-4059702-A ANTIVIRAL RICHARDSON-MERRELL INC. (US) 1977-11-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400503-A1 NOVEL PHOTOINITIATORS PPOX, CRY1, MAP1LC3A KMT2A 283/4885NPSR1 3272/4885SMN1; SMN2 4821/4885
US-20250276994-A1 CAP ANALOG FOR THE 5'-END OF EUKARYOTIC MESSENGER RNAS RNGTT, RNMT, NSUN2 KMT2A 2792/4885NPSR1 3427/4885SMN1; SMN2 1778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.