Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15542047 | 0.73 | KDM4E (0.49) | SMN1; SMN2ALDH1A1KDM4EMAPTCA12 | |
| SCHEMBL15541690 | 0.70 | KDM4E (0.53) | SMN1; SMN2ALDH1A1KDM4EMAPTCA12 | |
| SCHEMBL16863152 | 0.70 | KDM4E (0.53) | SMN1; SMN2ALDH1A1KDM4EMAPTCA12 | |
| SCHEMBL29950209 | 0.70 | KDM4E (0.53) | SMN1; SMN2ALDH1A1KDM4EMAPTCA12 | |
| SCHEMBL30129469 | 0.66 | ALDH1A1 (0.37) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL2761489 | 0.64 | CA12 (0.58) | SMN1; SMN2ALDH1A1KDM4EMAPTCA12 | |
| SCHEMBL8005054 | 0.62 | GAA (0.57) | ALDH1A1KDM4EMAPTCA12CA9 | |
| SCHEMBL26981026 | 0.62 | CA12 (0.56) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL20438074 | 0.61 | PPARG (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL17022691 | 0.61 | LMNA (0.56) | SMN1; SMN2ALDH1A1KDM4EMAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1230178-A | Polydithiocarbamate-containing macromolecules and use thereof for therapeutic and diagnostic applications | MEDINOX INC (US) | 1999-09-29 | — | — | CN | disclosed |