Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 2/20 | 0.44 |
| ▸ | CDK8 | P49336 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22191645 | 1.00 | MAP4K4 (0.46) | MAP4K4USP30CCNCCDK8DYRK1A | |
| SCHEMBL3464137 | 0.82 | L3MBTL1 (0.56) | USP30CCNCCDK8DYRK1ANFATC1 | |
| SCHEMBL22191807 | 0.79 | IDO1 (0.54) | MAP4K4DYRK1AMKNK1MKNK2NFATC1 | |
| SCHEMBL2686394 | 0.79 | IDO1 (0.54) | MAP4K4CCNCCDK8MKNK1MKNK2 | |
| SCHEMBL2687849 | 0.79 | PDPK1 (0.40) | USP30DYRK1AMKNK1MKNK2 | |
| SCHEMBL26606411 | 0.79 | MAP4K4 (0.49) | MAP4K4MKNK1MKNK2 | |
| SCHEMBL1856249 | 0.76 | PRMT5 (0.45) | PIK3CB | |
| SCHEMBL238785 | 0.76 | MKNK2 (0.47) | MAP4K4USP30DYRK1AMKNK1MKNK2 | |
| SCHEMBL22191743 | 0.76 | XDH (0.49) | USP30MKNK1MKNK2 | |
| SCHEMBL1143959 | 0.74 | ALPL (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4118087-A1 | SUBSTITUTED FURO[3,2-D]PYRIMIDINES AND USES THEREOF | Verge Analytics, Inc. (US) | 2023-01-18 | — | — | EP | disclosed |
| WO-2022261068-A1 | METHODS AND TREATMENT OF VIRAL INFECTION WITH SUBSTITUTED FURO-PYRIMIDINES | Verge Analytics, Inc. (US) | 2022-12-15 | — | — | WO | disclosed |