SCHEMBL30129649

SCHEMBL30129649

O=C(CNC(=O)OCC1c2ccccc2-c2ccccc21)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)NCO[C@@H](C(=O)O)C1CC1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 1/20 0.40
▸ TLR2 O60603 6/20 0.39
▸ KMT2A Q03164 1/20 0.38
▸ PTPN1 P18031 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25230181 1.00 OPRD1 (0.40) OPRD1TLR2KMT2APTPN1
SCHEMBL25944308 1.00 OPRD1 (0.40) OPRD1TLR2KMT2APTPN1
SCHEMBL31584331 0.89 KMT2A (0.39) OPRD1KMT2APTPN1
SCHEMBL30011678 0.88 KMT2A (0.47) OPRD1TLR2KMT2A
SCHEMBL31217959 0.88 KMT2A (0.47) OPRD1TLR2KMT2A
SCHEMBL23698366 0.88 KMT2A (0.47) OPRD1TLR2KMT2A
SCHEMBL27224594 0.88 KMT2A (0.47) OPRD1TLR2KMT2A
SCHEMBL30129765 0.88 KMT2A (0.47) OPRD1TLR2KMT2A
SCHEMBL31690598 0.88 PTPN1 (0.41) OPRD1KMT2APTPN1
SCHEMBL30918245 0.88 PTPN1 (0.41) OPRD1KMT2APTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230165969-A1 PHARMACEUTICAL COMPOSITION COMPRISING ANTIBODY DRUG CONJUGATE AND USE THEREOF JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2023-06-01 — — US disclosed
EP-4129345-A1 PHARMACEUTICAL COMPOSITION COMPRISING ANTIBODY DRUG CONJUGATE AND USE THEREOF Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2023-02-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165969-A1 PHARMACEUTICAL COMPOSITION COMPRISING ANTIBODY DRUG CONJUGATE AND USE THEREOF CFD, DDOST, HEXD OPRD1 2630/4885TLR2 1583/4885KMT2A 1497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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