Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31396442 | 0.91 | KMT2A (0.53) | KMT2ALMNAKCNH2GAADAO | |
| SCHEMBL20920832 | 0.91 | KMT2A (0.53) | KMT2ALMNAKCNH2GAADAO | |
| SCHEMBL22263183 | 0.84 | ALDH1A1 (0.53) | KMT2ALMNAKCNH2ALDH1A1CYP2C19 | |
| SCHEMBL22275730 | 0.83 | ALDH1A1 (0.51) | KMT2ALMNAALDH1A1CYP2C19GAA | |
| SCHEMBL30130108 | 0.82 | KMT2A (0.45) | KMT2ALMNAKCNH2GAADAO | |
| SCHEMBL20932660 | 0.82 | KMT2A (0.45) | KMT2ALMNAKCNH2GAADAO | |
| SCHEMBL30130190 | 0.81 | TSHR (0.43) | KMT2ALMNAKCNH2ALDH1A1GAA | |
| SCHEMBL20932772 | 0.81 | TSHR (0.43) | KMT2ALMNAKCNH2ALDH1A1GAA | |
| SCHEMBL22263114 | 0.81 | CYP1A2 (0.43) | KMT2ALMNAKCNH2ALDH1A1CYP2C19 | |
| SCHEMBL22263137 | 0.80 | MAPK1 (0.50) | KMT2ALMNAALDH1A1CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239452-A1 | IDO/TDO Inhibitor | CANBAS CO., LTD. (JP) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239452-A1 | IDO/TDO Inhibitor | IDO1, IDO2, TDO2 | KMT2A 800/4885LMNA 4867/4885KCNH2 2564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.