Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23727249 | 1.00 | ALDH1A1 (0.57) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Thiophanate SCHEMBL29398343 | 0.90 | ALDH1A1 (0.70) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Thiophanate SCHEMBL20842 | 0.90 | ALDH1A1 (0.70) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Thiophanate SCHEMBL7449541 | 0.88 | ALDH1A1 (0.68) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL12336304 | 0.85 | ALDH1A1 (0.64) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL11694452 | 0.85 | ALDH1A1 (0.79) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Thiophanate SCHEMBL10922494 | 0.85 | ALDH1A1 (0.79) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL23727265 | 0.85 | EPHX1 (0.65) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL1189632 | 0.85 | ALDH1A1 (0.77) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL11835690 | 0.84 | ALDH1A1 (0.62) | ALDH1A1LMNAHPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100008-A1 | PYRROLO [2,3-B]PYRIDINE-3-CARBOXAMIDE COMPOSITIONS AND METHODS FOR AMELIORATING HEARING LOSS | The Rockefeller University (US) | 2022-12-14 | — | — | EP | disclosed |