SCHEMBL30131270

SCHEMBL30131270

Cc1cccnc1OCCNC(=O)OC(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.49
CA1 P00915 5/20 0.49
CA2 P00918 5/20 0.49
CA9 Q16790 5/20 0.49
SSTR4 P31391 6/20 0.46
IDO1 P14902 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.44
SSTR1 P30872 3/20 0.43
PDK2 Q15119 1/20 0.43
CYP3A4 P08684 1/20 0.43
SCN9A Q15858 1/20 0.43
AKT1 P31749 1/20 0.42
BCHE P06276 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14728817 0.84 KDM4E (0.49) CA12CA1CA2CA9IDO1
SCHEMBL21383822 0.83 SSTR4 (0.45) SSTR4L3MBTL1
SCHEMBL17171586 0.82 MTNR1A (0.54) SSTR4L3MBTL1KDM4ECYP3A4
SCHEMBL21601421 0.81 L3MBTL1 (0.61) CA12CA1CA2CA9IDO1
SCHEMBL15869790 0.80 ALDH1A1 (0.55) CA12CA1CA2CA9IDO1
SCHEMBL15756423 0.78 CA12 (0.51) CA12CA1CA2CA9IDO1
SCHEMBL29420339 0.78 CA12 (0.51) CA12CA1CA2CA9IDO1
SCHEMBL6989294 0.78 CA12 (0.44) CA12CA1CA2CA9IDO1
SCHEMBL6991837 0.78 KDM4E (0.45) CA12CA1CA2CA9IDO1
SCHEMBL24192431 0.78 CA12 (0.42) CA12CA1CA2CA9IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 US disclosed
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR CA12 2875/4885CA1 1872/4885CA2 878/4885
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR CA12 2773/4885CA1 1791/4885CA2 812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.