Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.51 |
| ▸ | IL1B | P01584 | 7/20 | 0.44 |
| ▸ | CNR1 | P21554 | 6/20 | 0.42 |
| ▸ | CNR2 | P34972 | 6/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30131489 | 0.83 | P2RX7 (0.58) | P2RX7CNR1CNR2 | |
| SCHEMBL30250478 | 0.80 | MAPT (0.54) | P2RX7 | |
| SCHEMBL30875023 | 0.79 | P2RX7 (0.48) | P2RX7CNR1CNR2KCNA5PDE4A | |
| SCHEMBL31275734 | 0.77 | P2RX7 (0.41) | P2RX7 | |
| SCHEMBL20068866 | 0.77 | SSTR4 (0.49) | P2RX7CNR1CNR2 | |
| SCHEMBL20147919 | 0.76 | HTR4 (0.45) | P2RX7CNR1CNR2 | |
| SCHEMBL30875055 | 0.74 | EGLN2 (0.44) | — | |
| SCHEMBL20158754 | 0.73 | RET (0.45) | P2RX7CNR1CNR2 | |
| SCHEMBL30131408 | 0.73 | NPC1 (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30875025 | 0.72 | ALDH1A1 (0.43) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715898-A | Six-membered aryl or heteroaryl amide compound, composition and application thereof | 贝达药业股份有限公司 | 2024-03-15 | — | — | CN | claimed |
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | claimed |
| CN-117715898-A | Six-membered aryl or heteroaryl amide compound, composition and application thereof | 贝达药业股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |