Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 4/20 | 0.41 |
| ▸ | SLC2A2 | P11168 | 4/20 | 0.41 |
| ▸ | SLC2A3 | P11169 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL878705 | 0.82 | GCK (0.47) | SLC2A1SLC2A2SLC2A3KDM4EALDH1A1 | |
| SCHEMBL849766 | 0.79 | MAPT (0.46) | SLC2A1SLC2A2SLC2A3KDM4EALDH1A1 | |
| SCHEMBL12000897 | 0.79 | SLC2A1 (0.53) | SLC2A1SLC2A2SLC2A3KDM4EALDH1A1 | |
| SCHEMBL838812 | 0.77 | P2RX7 (0.44) | SLC2A1SLC2A2SLC2A3KDM4EALDH1A1 | |
| SCHEMBL25343546 | 0.76 | MAPT (0.52) | SLC2A1SLC2A2SLC2A3KDM4EALDH1A1 | |
| SCHEMBL838206 | 0.76 | SLC2A1 (0.56) | SLC2A1SLC2A2SLC2A3KDM4EALDH1A1 | |
| SCHEMBL838726 | 0.76 | GCK (0.44) | SLC2A1SLC2A2SLC2A3KDM4EALDH1A1 | |
| SCHEMBL6205196 | 0.76 | SLC2A1 (0.65) | SLC2A1SLC2A2SLC2A3KDM4ECYP1A2 | |
| SCHEMBL31337054 | 0.75 | ALDH1A1 (0.67) | SLC2A1SLC2A2SLC2A3KDM4EALDH1A1 | |
| SCHEMBL6282033 | 0.75 | ALDH1A1 (0.67) | SLC2A1SLC2A2SLC2A3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100015-A1 | COMBINATION THERAPY FOR TREATING MPS1 | Gain Therapeutics SA (CH) | 2022-12-14 | — | — | EP | disclosed |