Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 16/20 | 0.65 |
| ▸ | SLC2A3 | P11169 | 16/20 | 0.65 |
| ▸ | SLC2A2 | P11168 | 10/20 | 0.65 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25343546 | 0.87 | MAPT (0.52) | SLC2A1SLC2A3SLC2A2GSK3BMAPT | |
| SCHEMBL838296 | 0.85 | SLC2A1 (0.66) | SLC2A1SLC2A3SLC2A2GSK3BMAPT | |
| SCHEMBL838951 | 0.84 | SLC2A1 (0.65) | SLC2A1SLC2A3SLC2A2GSK3BMAPT | |
| SCHEMBL6224888 | 0.81 | GSK3B (0.62) | SLC2A1SLC2A3SLC2A2GSK3BMAPT | |
| Hydrochloric Acid SCHEMBL6205326 | 0.80 | GSK3B (0.61) | SLC2A1SLC2A3SLC2A2GSK3BMAPT | |
| SCHEMBL12000897 | 0.79 | SLC2A1 (0.53) | SLC2A1SLC2A3SLC2A2MAPTKDM4E | |
| SCHEMBL849766 | 0.79 | MAPT (0.46) | SLC2A1SLC2A3SLC2A2MAPTKDM4E | |
| SCHEMBL878705 | 0.79 | GCK (0.47) | SLC2A1SLC2A3SLC2A2MAPTKDM4E | |
| SCHEMBL8344599 | 0.79 | SLC2A1 (0.58) | SLC2A1SLC2A3SLC2A2GSK3BMAPT | |
| SCHEMBL838809 | 0.76 | ALDH1A1 (0.41) | SLC2A1SLC2A3SLC2A2GSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472739-A1 | IMIDAZOLE MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023148129-A1 | IMIDAZOLE MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-10 | — | — | WO | disclosed |
| EP-1551841-A1 | PYRAZOLOPYRIMIDINES AS KINASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004009602-A1 | PYRAZOLOPYRIMIDINES AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-29 | — | — | WO | disclosed |
| WO-2004009602-A1 | PYRAZOLOPYRIMIDINES AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-01-29 | — | — | WO | disclosed |