Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.35 |
| ▸ | HTR2C | P28335 | 6/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3028019 | 0.89 | MCHR1 (0.35) | MCHR1KCNH2HTR2CDRD3DRD2 | |
| SCHEMBL3666877 | 0.87 | NR1H2 (0.34) | MCHR1KCNH2HTR2CDRD3DRD2 | |
| SCHEMBL3026349 | 0.82 | MCHR1 (0.35) | MCHR1KCNH2HTR2CDRD3 | |
| SCHEMBL3025535 | 0.81 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL3804841 | 0.81 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL3028539 | 0.77 | KCNH2 (0.36) | MCHR1KCNH2HTR2C | |
| SCHEMBL3020655 | 0.77 | MCHR1 (0.34) | MCHR1KCNH2HTR2CDRD3DRD2 | |
| SCHEMBL2767755 | 0.76 | KDM4E (0.37) | KCNH2 | |
| SCHEMBL3016694 | 0.76 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL3016687 | 0.76 | KCNH2 (0.37) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197679-A1 | COMPOUNDS | GLAXO GROUP LIMITED | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197679-A1 | COMPOUNDS | NRDC, MRPL21, NISCH | MCHR1 4724/4885KCNH2 2445/4885HTR2C 2852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.