Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.33 |
| ▸ | HTR2C | P28335 | 6/20 | 0.33 |
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3020655 | 0.90 | MCHR1 (0.34) | MCHR1KCNH2HTR2CDRD3DRD2 | |
| SCHEMBL3013221 | 0.87 | MCHR1 (0.35) | MCHR1KCNH2HTR2CDRD3DRD2 | |
| SCHEMBL909708 | 0.79 | TACR1 (0.35) | KCNH2NR1H4 | |
| SCHEMBL3669003 | 0.78 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL11999874 | 0.77 | HSD11B1 (0.38) | NR1H4 | |
| SCHEMBL3028019 | 0.77 | MCHR1 (0.35) | MCHR1KCNH2HTR2CDRD3DRD2 | |
| SCHEMBL3013394 | 0.76 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL4101579 | 0.76 | DRD3 (0.45) | NR1H2DRD3DRD2 | |
| SCHEMBL4101573 | 0.76 | DRD3 (0.45) | NR1H2DRD3DRD2 | |
| SCHEMBL4107127 | 0.76 | DRD3 (0.45) | NR1H2DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139898-A1 | COMPOUNDS | Glaxo Group Limited (GB) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008128961-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |