Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3028019 | 0.92 | MCHR1 (0.35) | KCNH2 | |
| SCHEMBL3021131 | 0.86 | KCNH2 (0.44) | KCNH2SLC2A1 | |
| SCHEMBL3020868 | 0.86 | KCNH2 (0.44) | KCNH2SLC2A1 | |
| SCHEMBL3013221 | 0.81 | MCHR1 (0.35) | KCNH2 | |
| SCHEMBL3020655 | 0.80 | MCHR1 (0.34) | KCNH2 | |
| SCHEMBL3026349 | 0.75 | MCHR1 (0.35) | KCNH2 | |
| SCHEMBL3028539 | 0.72 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL3025535 | 0.71 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL3666877 | 0.70 | NR1H2 (0.34) | KCNH2 | |
| SCHEMBL2767755 | 0.69 | KDM4E (0.37) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139898-A1 | COMPOUNDS | Glaxo Group Limited (GB) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008128961-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |