Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.33 |
| ▸ | HTR2C | P28335 | 6/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666877 | 0.90 | NR1H2 (0.34) | MCHR1KCNH2HTR2CDRD2DRD3 | |
| SCHEMBL3028019 | 0.87 | MCHR1 (0.35) | MCHR1KCNH2HTR2CDRD2DRD3 | |
| SCHEMBL3804841 | 0.80 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL909708 | 0.79 | TACR1 (0.35) | KCNH2NR1H4 | |
| SCHEMBL3669003 | 0.77 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL3013221 | 0.77 | MCHR1 (0.35) | MCHR1KCNH2HTR2CDRD2DRD3 | |
| SCHEMBL11999874 | 0.77 | HSD11B1 (0.38) | NR1H4 | |
| SCHEMBL4100155 | 0.76 | DRD3 (0.45) | MCHR1DRD2DRD3 | |
| SCHEMBL4110551 | 0.76 | DRD3 (0.45) | MCHR1DRD2DRD3 | |
| SCHEMBL4100163 | 0.76 | DRD3 (0.45) | MCHR1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197679-A1 | COMPOUNDS | GLAXO GROUP LIMITED | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197679-A1 | COMPOUNDS | NRDC, MRPL21, NISCH | MCHR1 4724/4885KCNH2 2445/4885HTR2C 2852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.