Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.72 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20554746 | 1.00 | MAOB (0.72) | MAOBPDE4BALDH1A1KDM4ENPC1 | |
| SCHEMBL2319848 | 0.84 | ALDH1A1 (0.67) | MAOBPDE4BALDH1A1KDM4ENPC1 | |
| SCHEMBL31260255 | 0.81 | MAOB (0.64) | MAOBPDE4BALDH1A1KDM4ENPC1 | |
| SCHEMBL224979 | 0.81 | MAOB (0.64) | MAOBPDE4BALDH1A1KDM4ENPC1 | |
| SCHEMBL9825262 | 0.77 | MAOB (0.67) | MAOBPDE4BALDH1A1KDM4ENPC1 | |
| SCHEMBL2317705 | 0.77 | MAOB (0.59) | MAOBPDE4BALDH1A1KDM4ENPC1 | |
| SCHEMBL10403215 | 0.76 | MAOB (0.57) | MAOBPDE4BALDH1A1KDM4ENPC1 | |
| SCHEMBL10609734 | 0.76 | MAOB (0.67) | MAOBPDE4BALDH1A1KDM4ENPC1 | |
| SCHEMBL10403216 | 0.76 | MAOB (0.67) | MAOBPDE4BALDH1A1KDM4ENPC1 | |
| SCHEMBL10610580 | 0.76 | MAOB (0.67) | MAOBALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | disclosed |