Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31260255 | 1.00 | MAOB (0.64) | MAOBALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL6086511 | 0.88 | KDM4E (0.65) | MAOBALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10403860 | 0.84 | MAOB (0.67) | MAOBALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL2317705 | 0.82 | MAOB (0.59) | MAOBALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL31260293 | 0.82 | ALDH1A1 (0.57) | MAOBALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL29191764 | 0.81 | ALDH1A1 (0.59) | MAOBALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL10403216 | 0.81 | MAOB (0.67) | MAOBALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL30132471 | 0.81 | MAOB (0.72) | MAOBALDH1A1KDM4ELMNANPC1 | |
| SCHEMBL10403215 | 0.81 | MAOB (0.57) | MAOBALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL20554746 | 0.81 | MAOB (0.72) | MAOBALDH1A1KDM4ELMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4474446-B1 | ELECTROCHROMIC COMPOUNDS, COMPOSITIONS AND DEVICES COMPRISING THE SAME | ESSILOR INT (FR) | 2025-12-17 | — | — | EP | disclosed |
| US-20250122152-A1 | KAT6 Inhibitors | BEIGENE SWITZERLAND GMBH (CH) | 2025-04-17 | — | — | US | disclosed |
| WO-2025068943-A1 | KAT6 INHIBITORS | BEIGENE SWITZERLAND GMBH (CH) | 2025-04-03 | — | — | WO | disclosed |
| WO-2024251948-A1 | ELECTROCHROMIC COMPOUNDS, COMPOSITIONS AND DEVICES COMPRISING THE SAME | ESSILOR INTERNATIONAL (FR) | 2024-12-12 | — | — | WO | disclosed |
| EP-4474446-A1 | ELECTROCHROMIC COMPOUNDS, COMPOSITIONS AND DEVICES COMPRISING THE SAME | Essilor International (FR) | 2024-12-11 | — | — | EP | disclosed |
| EP-3305794-B1 | SELECTIVE MODULATORS OF THE ACTIVITY OF THE GPR55 RECEPTOR: CHROMENOPYRAZOLE DERIVATIVES | CONSEJO SUPERIOR INVESTIGACION (ES) | 2020-02-05 | — | — | EP | disclosed |
| US-10435412-B2 | Selective modulators of the activity of the GPR55 receptor: chromenopyrazole derivatives | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2019-10-08 | — | — | US | disclosed |
| US-20180201620-A1 | Selective Modulators of the Activity of the GPR55 Receptor: Chromenopyrazole Derivatives | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) | 2018-07-19 | — | — | US | disclosed |
| US-20180201620-A1 | Selective Modulators of the Activity of the GPR55 Receptor: Chromenopyrazole Derivatives | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) | 2018-07-19 | — | — | US | disclosed |
| WO-2016177922-A1 | SELECTIVE MODULATORS OF THE ACTIVITY OF THE GPR55 RECEPTOR: CHROMENOPYRAZOLE DERIVATIVES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENIFICAS (CSIC) (ES) | 2016-11-10 | — | — | WO | disclosed |
| US-4866089-A | 7-ALKOXY-8-METHOXY-2,2-DIMETHYL-2H-CHROMENES; INSECTICIDES, NEMATOCIDES | ALKALOIDA VEGYESZETI GYAR (HU) | 1989-09-12 | — | — | US | disclosed |
| US-4803203-A | SCHIZOPHRENIA, NEUOLEPTIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0277611-A2 | Alkyl-substituted N-benzopyranyl lactames, process for their preparation, their use and pharmaceutical preparations on the basis of these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-10 | — | — | EP | disclosed |
| EP-0277612-A2 | Substituted 3,4-dihydro-2H-benzopyranes, process for their preparation, their use and pharmaceutical preparations based on these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-10 | — | — | EP | disclosed |
| EP-0271550-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM | ALKALOIDA VEGYéSZETI GYáR (HU) | 1988-06-22 | — | — | EP | disclosed |
| WO-1988000197-A1 | BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES AND COMPOSITIONS CONTAINING THEM | ALKALOIDA VEGYE^´SZETI GYA^´R (HU) | 1988-01-14 | — | — | WO | disclosed |
| US-4704390-A | SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1987-11-03 | — | — | US | disclosed |
| EP-0237781-A2 | Phenyl and heterocyclic tetrahydropyridyl and piperazinyl alkoxy-benzheterocyclic compounds as antipsychotic agents | WARNER-LAMBERT COMPANY (US) | 1987-09-23 | — | — | EP | disclosed |
| EP-0129636-A1 | Process for the preparation of chromen derivatives | ALKALOIDA VEGYéSZETI GYáR (HU) | 1985-01-02 | — | — | EP | disclosed |
| US-4261988-A | ANTICHOLESTEROL AGENTS USED IN ANIMAL HUSBANDRY | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180201620-A1 | Selective Modulators of the Activity of the GPR55 Receptor: Chromenopyrazole Derivatives | GPR55, GPR35, CNR2 | MAOB 3811/4885ALDH1A1 3984/4885KDM4E 2300/4885 |
| US-20250122152-A1 | KAT6 Inhibitors | KAT6A, KAT6B, KAT7 | MAOB 1231/4885ALDH1A1 3555/4885KDM4E 948/4885 |
| US-10435412-B2 | Selective modulators of the activity of the GPR55 receptor: chromenopyrazole derivatives | GPR55, GPR35, CNR2 | MAOB 3811/4885ALDH1A1 3984/4885KDM4E 2300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.