Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20554915 | 1.00 | KDM4E (0.38) | KDM4EMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20554176 | 0.86 | GRM4 (0.41) | KDM4EMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20554745 | 0.82 | SLC40A1 (0.37) | KDM4ESMN1; SMN2GAAMAOAMAOB | |
| SCHEMBL30132530 | 0.82 | SLC40A1 (0.37) | KDM4ESMN1; SMN2GAAMAOAMAOB | |
| SCHEMBL20554046 | 0.81 | KDM4E (0.43) | KDM4EMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30132678 | 0.80 | SLC6A4 (0.43) | KDM4EMAPK1GAAMAOAMAOB | |
| SCHEMBL20554811 | 0.80 | SLC6A4 (0.43) | KDM4EMAPK1GAAMAOAMAOB | |
| SCHEMBL20554667 | 0.79 | BRD4 (0.35) | KDM4EMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20554693 | 0.78 | BRD4 (0.46) | KDM4EMAPTMAOAMAOBRAB9A | |
| SCHEMBL20554706 | 0.78 | ALDH1A1 (0.44) | KDM4EMAPTALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | disclosed |