Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20554811 | 1.00 | SLC6A4 (0.43) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL20554176 | 0.86 | GRM4 (0.41) | SLC6A4HTR2AKCNH2SLC6A2SLC6A3 | |
| SCHEMBL20608927 | 0.82 | L3MBTL1 (0.46) | MAOBAOC3KDM4EL3MBTL1 | |
| SCHEMBL30132569 | 0.82 | L3MBTL1 (0.46) | MAOBAOC3KDM4EL3MBTL1 | |
| SCHEMBL20554915 | 0.80 | KDM4E (0.38) | MAOBKDM4EMAPK1L3MBTL1GAA | |
| SCHEMBL30132632 | 0.80 | KDM4E (0.38) | MAOBKDM4EMAPK1L3MBTL1GAA | |
| SCHEMBL20554046 | 0.78 | KDM4E (0.43) | SLC6A4SLC6A2SLC6A3MAOBKDM4E | |
| SCHEMBL30132665 | 0.78 | CYP19A1 (0.51) | CYP19A1EGFRLCKRHEBKDM4E | |
| SCHEMBL20554722 | 0.78 | CYP19A1 (0.51) | CYP19A1EGFRLCKRHEBKDM4E | |
| SCHEMBL20554260 | 0.78 | L3MBTL1 (0.41) | SLC6A4HTR2AKCNH2KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | disclosed |