Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20608927 | 1.00 | L3MBTL1 (0.46) | L3MBTL1KDM4EBRD4MAPTNPSR1 | |
| SCHEMBL20554693 | 0.87 | BRD4 (0.46) | L3MBTL1KDM4EBRD4MAPTMAOB | |
| SCHEMBL20554811 | 0.82 | SLC6A4 (0.43) | L3MBTL1KDM4EMAOBAOC3 | |
| SCHEMBL30132678 | 0.82 | SLC6A4 (0.43) | L3MBTL1KDM4EMAOBAOC3 | |
| SCHEMBL20554667 | 0.81 | BRD4 (0.35) | L3MBTL1KDM4EBRD4MAPTNPSR1 | |
| SCHEMBL26964320 | 0.80 | L3MBTL1 (0.51) | L3MBTL1KDM4EMAPTNPSR1KMT2A | |
| SCHEMBL20554198 | 0.80 | SCN9A (0.43) | L3MBTL1BRD4MAPTMAOBAOC3 | |
| SCHEMBL20554646 | 0.79 | ALDH1A1 (0.44) | L3MBTL1KDM4EMAPTNPSR1KMT2A | |
| SCHEMBL20554745 | 0.79 | SLC40A1 (0.37) | L3MBTL1KDM4EBRD4MAOBSCN9A | |
| SCHEMBL30132530 | 0.79 | SLC40A1 (0.37) | L3MBTL1KDM4EBRD4MAOBSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770211-B | Alpha, beta unsaturated amide compound | 协和麒麟株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-108430972-B | Alpha, beta-unsaturated amide compound | 协和麒麟株式会社 | 2022-12-27 | — | — | CN | disclosed |