Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25315001 | 1.00 | MEN1 (0.37) | MEN1PGRKMT2AALDH1A1ALDH1A3 | |
| SCHEMBL30227287 | 0.81 | ALDH1A1 (0.44) | MEN1PGRKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL25312276 | 0.81 | ALDH1A1 (0.44) | MEN1PGRKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30132785 | 0.80 | PGR (0.52) | MEN1PGRKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL25314386 | 0.80 | PGR (0.52) | MEN1PGRKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL25312867 | 0.78 | MEN1 (0.34) | MEN1PGRKMT2A | |
| SCHEMBL30227489 | 0.78 | MEN1 (0.34) | MEN1PGRKMT2A | |
| SCHEMBL25312905 | 0.78 | AR (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL30227657 | 0.78 | AR (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL25312049 | 0.72 | PGR (0.41) | MEN1PGRKMT2AALDH1A1ALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143182-B1 | NOVEL COMPOUNDS USEFUL AS POLY(ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2024-12-11 | — | — | EP | disclosed |
| CN-115485271-A | Novel compounds as inhibitors of poly (ADP-ribose) polymerase (PARP) | 理森制药股份公司 | 2022-12-16 | — | — | CN | disclosed |