Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | PTH1R | Q03431 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25312867 | 1.00 | MEN1 (0.34) | MEN1KMT2APGRPTH1RRAB9A | |
| SCHEMBL25314259 | 0.82 | PGR (0.47) | MEN1KMT2APGRPTH1RSCN9A | |
| SCHEMBL30132808 | 0.82 | PGR (0.47) | MEN1KMT2APGRPTH1RSCN9A | |
| SCHEMBL30132770 | 0.78 | MEN1 (0.37) | MEN1KMT2APGR | |
| SCHEMBL25315001 | 0.78 | MEN1 (0.37) | MEN1KMT2APGR | |
| SCHEMBL25313095 | 0.78 | PTH1R (0.34) | PTH1RRAB9A | |
| SCHEMBL30227445 | 0.78 | PTH1R (0.34) | PTH1RRAB9A | |
| SCHEMBL25313606 | 0.77 | MEN1 (0.39) | MEN1KMT2APGRSCN9A | |
| SCHEMBL29565622 | 0.77 | MEN1 (0.39) | MEN1KMT2APGRSCN9A | |
| SCHEMBL25312276 | 0.72 | ALDH1A1 (0.44) | MEN1KMT2APGRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143182-A1 | NOVEL COMPOUNDS USEFUL AS POLY(ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS | Rhizen Pharmaceuticals AG (CH) | 2023-03-08 | — | — | EP | disclosed |