Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 12/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 12/20 | 0.48 |
| ▸ | WNT1 | P04628 | 8/20 | 0.48 |
| ▸ | FYN | P06241 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109233 | 0.84 | LMNA (0.54) | GSK3BDYRK1AWNT1LMNAHPGD | |
| SCHEMBL30133188 | 0.79 | LMNA (0.67) | FYNLMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL928947 | 0.73 | GSK3B (0.48) | GSK3BDYRK1AWNT1SMN1; SMN2 | |
| SCHEMBL23549882 | 0.73 | GSK3B (0.44) | GSK3BDYRK1AWNT1 | |
| SCHEMBL10298806 | 0.72 | HTR7 (0.46) | GSK3BDYRK1AWNT1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28735083 | 0.71 | GSK3B (0.47) | GSK3BDYRK1AWNT1LMNAHPGD | |
| SCHEMBL16836286 | 0.71 | ROCK2 (0.48) | GSK3BDYRK1AWNT1ROCK2 | |
| Hydrochloric Acid SCHEMBL28382225 | 0.70 | GSK3B (0.43) | GSK3BDYRK1AWNT1FYN | |
| SCHEMBL19546542 | 0.69 | GSK3B (0.69) | GSK3BDYRK1AWNT1 | |
| SCHEMBL930918 | 0.69 | GSK3B (0.40) | GSK3BDYRK1AWNT1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605596-A | Compositions and methods for inducible alternative splicing modulation of gene expression | 费城儿童医院（US） | 2023-01-13 | — | — | CN | disclosed |