Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | CD44 | P16070 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL587771 | 1.00 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA4CHRNA2HTR2A | |
| SCHEMBL21326130 | 0.93 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA4CHRNA2HTR2A | |
| Hydrochloric Acid SCHEMBL25324792 | 0.92 | CHRNB2 (0.43) | CHRNB2CHRNB4CHRNA4CHRNA2DRD2 | |
| SCHEMBL29640882 | 0.85 | CHRNB2 (0.42) | CHRNB2CHRNB4CHRNA4CHRNA2 | |
| SCHEMBL10067119 | 0.77 | ASIC3 (0.43) | HTR2CHTR2BASIC3DRD2DRD3 | |
| SCHEMBL7238336 | 0.76 | NOS3 (0.50) | CHRNB2CHRNB4CHRNA4CHRNA2HTR2A | |
| SCHEMBL27884524 | 0.76 | NOS3 (0.45) | CHRNB2CHRNB4CHRNA4CHRNA2 | |
| SCHEMBL17892754 | 0.74 | RYR2 (0.56) | CHRNB2CHRNB4CHRNA4CHRNA2 | |
| SCHEMBL1721036 | 0.74 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA4CHRNA2DRD2 | |
| SCHEMBL3034518 | 0.74 | CHRNB2 (0.42) | CHRNB2CHRNB4CHRNA4CHRNA2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605475-B | Immunosuppressant, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-115605475-A | Immunosuppressant, preparation method and application thereof | 上海和誉生物医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |