Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371340 | 1.00 | SIGMAR1 (0.46) | SIGMAR1CHRNB2CHRNA4HRH3NAMPT | |
| SCHEMBL8271969 | 0.93 | SIGMAR1 (0.46) | SIGMAR1CHRNB2CHRNA4HRH3NAMPT | |
| SCHEMBL7878390 | 0.85 | MITF (0.43) | SIGMAR1CHRNB2CHRNA4NAMPTMITF | |
| SCHEMBL29852295 | 0.85 | MAPT (0.45) | SIGMAR1HRH3NAMPTPDGFRBKDR | |
| SCHEMBL21882782 | 0.84 | ADORA2A (0.42) | SIGMAR1CHRNB2CHRNA4NAMPTPDGFRB | |
| SCHEMBL19163823 | 0.78 | HRH3 (0.39) | HRH3MITFALDH1A1LMNARAB9A | |
| SCHEMBL9965909 | 0.78 | MAOA (0.55) | SIGMAR1CHRNB2CHRNA4 | |
| SCHEMBL1083820 | 0.76 | MAOA (0.57) | HRH3ALDH1A1LMNA | |
| SCHEMBL30561536 | 0.76 | MAOA (0.57) | HRH3ALDH1A1LMNA | |
| SCHEMBL18417276 | 0.76 | NAMPT (0.49) | SIGMAR1HRH3NAMPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605475-B | Immunosuppressant, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-115605475-A | Immunosuppressant, preparation method and application thereof | 上海和誉生物医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |