Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15974121 | 1.00 | NR3C1 (0.36) | NR3C1IDO1NOTUMNR3C2HTT | |
| SCHEMBL29519382 | 0.87 | NR3C1 (0.36) | NR3C1IDO1NOTUMNR3C2HTT | |
| SCHEMBL19693724 | 0.87 | NR3C1 (0.36) | NR3C1IDO1NOTUMNR3C2HTT | |
| SCHEMBL278305 | 0.84 | PTGS1 (0.39) | NR3C1IDO1HTTMEN1MAPT | |
| SCHEMBL15933087 | 0.83 | NOTUM (0.36) | NR3C1IDO1NOTUMNR3C2EPAS1 | |
| SCHEMBL624437 | 0.82 | IDO1 (0.46) | IDO1NOTUMHTTEPHX1MEN1 | |
| SCHEMBL29572164 | 0.82 | IDO1 (0.46) | IDO1NOTUMHTTEPHX1MEN1 | |
| SCHEMBL10322751 | 0.81 | MEN1 (0.39) | NR3C1NR3C2MEN1KMT2APTGS1 | |
| SCHEMBL29519425 | 0.81 | MEN1 (0.39) | NR3C1NR3C2MEN1KMT2APTGS1 | |
| SCHEMBL19926591 | 0.75 | PKM (0.39) | NR3C1HTTEPHX1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119033-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118271284-A | Estrogen receptor modulators and uses thereof | 江苏威凯尔医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| EP-4380936-A1 | PYRAZOLOPYRIDINONE COMPOUNDS | BeiGene, Ltd. (KY) | 2024-06-12 | — | — | EP | disclosed |
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023011456-A1 | PYRAZOLOPYRIDINONE COMPOUNDS | BEIGENE, LTD. (KY) | 2023-02-09 | — | — | WO | disclosed |