SCHEMBL30134236

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30353262	0.83	KDM4E (0.54)	KDM4ERARARARBRARGRXRA
	SCHEMBL2240683	0.83	RARB (0.64)	KDM4ERARARARBRARGRXRA
	SCHEMBL4421853	0.79	KDM4E (0.50)	KDM4ERARARARBRARGRXRA
	SCHEMBL11926956	0.76	BACE1 (0.42)	AKR1B1MAPT
	SCHEMBL7681598	0.75	KDM4E (0.46)	KDM4ERARARARBRARGRXRA
	SCHEMBL29249340	0.75	RARB (0.61)	RARARARBRARGRXRACYP26A1
	SCHEMBL29249339	0.75	RARB (0.61)	RARARARBRARGRXRACYP26A1
	SCHEMBL13668239	0.74	KDM4E (0.50)	KDM4ERARARARBRARGRXRA
	SCHEMBL9144307	0.74	KDM4E (0.54)	KDM4ERARARARBRARGRXRA
	SCHEMBL102971	0.73	KDM4E (0.89)	KDM4ENPC1MAPTRAB9ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.