Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31472832 | 0.92 | PTPN1 (0.44) | PTPN1GRB2MDM2MDM4TP53 | |
| SCHEMBL29702381 | 0.90 | MDM2 (0.49) | MDM2MDM4TP53 | |
| SCHEMBL30425989 | 0.88 | REN (0.39) | PTPN1GRB2MDM2 | |
| SCHEMBL30425912 | 0.88 | PTPN1 (0.51) | PTPN1GRB2MDM2CTSLCTSK | |
| Hydrochloric Acid SCHEMBL31450109 | 0.86 | MDM2 (0.44) | MDM2MDM4TP53 | |
| SCHEMBL30424739 | 0.83 | PTPN1 (0.47) | PTPN1GRB2MDM2PSMB8PSMB9 | |
| SCHEMBL31472817 | 0.83 | PTPN1 (0.39) | PTPN1GRB2MDM2MDM4TP53 | |
| SCHEMBL31472825 | 0.83 | PTPN1 (0.39) | PTPN1GRB2MDM2MDM4TP53 | |
| SCHEMBL29670271 | 0.83 | MDM4 (0.49) | PTPN1MDM2MDM4TP53 | |
| SCHEMBL31472821 | 0.82 | PTPN1 (0.39) | PTPN1GRB2MDM2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240287106-A1 | Method for Producing Fluorescent Probe Library Using Solid-Phase Extraction and Method of Measuring Enzyme Activity Using Same | RIKEN (JP) | 2024-08-29 | — | — | US | disclosed |
| EP-4353731-A1 | METHOD FOR PRODUCING FLUORESCENT PROBE LIBRARY USING SOLID-PHASE EXTRACTION AND METHOD OF MEASURING ENZYME ACTIVITY USING SAME | The University of Tokyo (JP) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022260135-A1 | METHOD FOR PRODUCING FLUORESCENT PROBE LIBRARY USING SOLID-PHASE EXTRACTION AND METHOD OF MEASURING ENZYME ACTIVITY USING SAME | 国立大学法人 東京大学 | 2022-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240287106-A1 | Method for Producing Fluorescent Probe Library Using Solid-Phase Extraction and Method of Measuring Enzyme Activity Using Same | NOTUM, GUSB, RNGTT | PTPN1 4506/4885GRB2 3488/4885MDM2 2325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.