SCHEMBL29670271

SCHEMBL29670271

CC(C)C[C@H](NC(=O)[C@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.49
▸ TP53 P04637 3/20 0.49
▸ NMBR P28336 1/20 0.48
▸ PTPN1 P18031 5/20 0.47
▸ SIRT2 Q8IXJ6 6/20 0.44
▸ MDM2 Q00987 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29368020 0.90 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL13227674 0.90 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL30433831 0.90 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL12994493 0.90 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL1737899 0.90 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL29399601 0.89 SIRT2 (0.49) MDM4TP53NMBRSIRT2
SCHEMBL28913051 0.89 SIRT2 (0.49) MDM4TP53NMBRSIRT2
SCHEMBL28913050 0.89 SIRT2 (0.49) MDM4TP53NMBRSIRT2
SCHEMBL28625947 0.87 MDM2 (0.52) MDM4TP53SIRT2MDM2
SCHEMBL30434660 0.87 MDM2 (0.52) MDM4TP53SIRT2MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12240871-B2 Method for producing peptide compound NISSAN CHEMICAL CORPORATION (JP) 2025-03-04 — — US disclosed
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240871-B2 Method for producing peptide compound NGLY1, NPPA, NPEPPS MDM4 2239/4885TP53 2675/4885NMBR 947/4885
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NGLY1, NPPA, NPEPPS MDM4 2239/4885TP53 2675/4885NMBR 947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback