Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958070 | 1.00 | LMNA (0.43) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL15428186 | 0.91 | GRM5 (0.45) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL25273234 | 0.73 | ALDH1A1 (0.49) | LMNAKMT2AMEN1ALDH1A1TRIM24 | |
| SCHEMBL29417095 | 0.73 | TRIM24 (0.43) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL31587369 | 0.72 | MEN1 (0.50) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL9699037 | 0.72 | LMNA (0.50) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL193992 | 0.71 | KMT2A (0.50) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL29880146 | 0.71 | KMT2A (0.48) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL21246857 | 0.71 | KCNH2 (0.43) | LMNATSHRCYP1A2GRM5PTPN11 | |
| SCHEMBL4607978 | 0.71 | CYP1A2 (0.50) | KMT2AMEN1ALDH1A1CYP1A2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504953-A | Preparation method of 3-isocoumarin chromone compound | 昆明理工大学 | 2022-12-23 | — | — | CN | disclosed |