Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16612459 | 0.78 | TSHR (0.41) | TSHRHSD17B10CYP1A2MAPTHTT | |
| SCHEMBL21527518 | 0.71 | LMNA (0.41) | TSHRHSD17B10CYP1A2ALDH1A1KMT2A | |
| SCHEMBL8172259 | 0.69 | CYP1A2 (0.47) | TSHRHSD17B10CYP1A2MAPTALDH1A1 | |
| SCHEMBL12480441 | 0.67 | HTT (0.53) | TSHRHSD17B10CYP1A2MAPTHTT | |
| SCHEMBL4421203 | 0.65 | ALDH1A1 (0.62) | TSHRHSD17B10CYP1A2MAPTHTT | |
| SCHEMBL6924804 | 0.64 | GSK3A (0.41) | TSHRHSD17B10CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL736634 | 0.62 | GSK3A (0.40) | TSHRHSD17B10CYP1A2MAPTALDH1A1 | |
| SCHEMBL4522976 | 0.61 | CYP1A2 (0.42) | TSHRHSD17B10CYP1A2MAPTHTT | |
| SCHEMBL4533135 | 0.61 | CYP1A2 (0.42) | TSHRHSD17B10CYP1A2MAPTHTT | |
| SCHEMBL932446 | 0.60 | POLB (0.53) | TSHRHSD17B10MAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022216098-A1 | NOVEL LRRK2 INHIBITOR | 주식회사 스탠다임 | 2022-10-13 | — | — | WO | disclosed |