Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30135518 | 0.78 | TSHR (0.42) | TSHRHSD17B10CYP1A2POLBKMT2A | |
| SCHEMBL9879740 | 0.73 | RAB9A (0.42) | TSHRHSD17B10CYP1A2KMT2AALDH1A1 | |
| SCHEMBL12480441 | 0.66 | HTT (0.53) | TSHRHSD17B10CYP1A2POLBALDH1A1 | |
| SCHEMBL6924804 | 0.66 | GSK3A (0.41) | TSHRHSD17B10CYP1A2POLBKMT2A | |
| SCHEMBL8172259 | 0.65 | CYP1A2 (0.47) | TSHRHSD17B10CYP1A2POLBKMT2A | |
| SCHEMBL736634 | 0.65 | GSK3A (0.40) | TSHRHSD17B10CYP1A2KMT2AGSK3A | |
| SCHEMBL1625119 | 0.65 | RAB9A (0.40) | TSHRHSD17B10CYP1A2KMT2AALDH1A1 | |
| SCHEMBL21527518 | 0.65 | LMNA (0.41) | TSHRHSD17B10CYP1A2POLBKMT2A | |
| SCHEMBL4421203 | 0.64 | ALDH1A1 (0.62) | TSHRHSD17B10CYP1A2KMT2AALDH1A1 | |
| SCHEMBL3942676 | 0.62 | POLB (0.47) | TSHRHSD17B10CYP1A2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857387-A1 | Process for manufacturing 1,6-dihydro-6-oxo-4-pyridazine carboxylic acid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |
| EP-2857387-A1 | Process for manufacturing 1,6-dihydro-6-oxo-4-pyridazine carboxylic acid | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-08 | — | — | EP | disclosed |