Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374970 | 1.00 | SLC22A12 (0.50) | SLC22A12LMNAALKKDM4EALDH1A1 | |
| SCHEMBL7372580 | 0.91 | SLC22A12 (0.44) | SLC22A12LMNAALKKDM4EALDH1A1 | |
| SCHEMBL7367248 | 0.86 | LMNA (0.60) | SLC22A12LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7664986 | 0.81 | GAA (0.51) | SLC22A12LMNAALKKDM4EALDH1A1 | |
| SCHEMBL30717956 | 0.81 | L3MBTL1 (0.51) | SLC22A12LMNAALKKDM4EALDH1A1 | |
| SCHEMBL1998421 | 0.81 | L3MBTL1 (0.51) | SLC22A12LMNAALKKDM4EALDH1A1 | |
| SCHEMBL29996665 | 0.81 | LMNA (0.50) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2748318 | 0.81 | LMNA (0.50) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2810092 | 0.81 | LMNA (0.50) | LMNAKDM4EALDH1A1NPC1L3MBTL1 | |
| SCHEMBL26965980 | 0.79 | PREP (0.57) | SLC22A12LMNAALKKDM4EPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978509-A | FAP receptor-targeted PET tracer and preparation method thereof | 浙江大学 | 2024-11-19 | — | — | CN | claimed |
| CN-118978509-A | FAP receptor-targeted PET tracer and preparation method thereof | 浙江大学 | 2024-11-19 | — | — | CN | disclosed |
| EP-4373529-A1 | FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND USE THEREOF | 3B Pharmaceuticals GmbH (DE) | 2024-05-29 | — | — | EP | disclosed |
| WO-2023002045-A1 | FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND USE THEREOF | 3B PHARMACEUTICALS GMBH (DE) | 2023-01-26 | — | — | WO | disclosed |