SCHEMBL2810092

SCHEMBL2810092

O=C(O)c1ccc2c(C(=O)O)ccnc2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
PTPN1 P18031 1/20 0.50
KDM4A O75164 4/20 0.47
KDM4C Q9H3R0 4/20 0.47
KDM5A P29375 4/20 0.47
KDM5B Q9UGL1 4/20 0.47
KDM4E B2RXH2 4/20 0.47
EGLN1 Q9GZT9 2/20 0.47
HIF1AN Q9NWT6 2/20 0.47
KDM6B O15054 2/20 0.47
KDM5C P41229 2/20 0.47
KDM2A Q9Y2K7 2/20 0.47
KDM3A Q9Y4C1 2/20 0.47
TET3 O43151 1/20 0.47
BBOX1 O75936 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
ASPH Q12797 1/20 0.47
KDM4D Q6B0I6 1/20 0.47
TET2 Q6N021 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10464811 0.86 LMNA (0.62) LMNAPTPN1KDM4AKDM4CKDM5A
SCHEMBL487232 0.82 KDM4E (0.47) KDM4AKDM4CKDM5AKDM5BKDM4E
SCHEMBL29996665 0.82 LMNA (0.50) LMNAKDM4AKDM4CKDM5AKDM5B
SCHEMBL2748318 0.82 LMNA (0.50) LMNAKDM4AKDM4CKDM5AKDM5B
SCHEMBL5761766 0.81 LMNA (0.53) LMNAKDM4AKDM4CKDM5AKDM5B
SCHEMBL1732368 0.81 SMYD3 (0.49) KDM4AKDM4CKDM5AKDM5BKDM4E
SCHEMBL437621 0.81 NR4A2 (0.54) LMNAKDM4AKDM4CKDM5AKDM5B
SCHEMBL7370900 0.81 LMNA (0.49) LMNAKDM4AKDM4CKDM5AKDM5B
SCHEMBL30135541 0.81 SLC22A12 (0.50) LMNAKDM4AKDM4CKDM5AKDM5B
SCHEMBL5762904 0.81 CYP1A2 (0.58) LMNAKDM4CKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 WO disclosed
CN-105755480-A Efficient acidic cleaner 江苏筑磊电子科技有限公司 2016-07-13 CN disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed
US-4968803-A FLUORINE AS OXIDANT ALLIED-SIGNAL INC. (US) 1990-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 LMNA 1561/4885PTPN1 1478/4885KDM4A 2848/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB LMNA 72/4885PTPN1 2600/4885KDM4A 2509/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA LMNA 833/4885PTPN1 1680/4885KDM4A 1764/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA LMNA 966/4885PTPN1 1734/4885KDM4A 3320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.