Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 12/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NSD2 | O96028 | 1/20 | 0.54 |
| ▸ | PREP | P48147 | 5/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.51 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30135587 | 0.84 | NSD2 (0.62) | FAPNSD2PREPDPP7PITRM1 | |
| SCHEMBL15129718 | 0.84 | NSD2 (0.62) | FAPNSD2PREPDPP7PITRM1 | |
| SCHEMBL22567641 | 0.83 | FAP (0.48) | FAPMEN1KMT2APREPDPP9 | |
| SCHEMBL24934260 | 0.83 | FAP (0.48) | FAPMEN1KMT2APREPDPP9 | |
| SCHEMBL31505454 | 0.83 | FAP (0.48) | FAPMEN1KMT2APREPDPP9 | |
| SCHEMBL12903049 | 0.82 | NSD2 (0.59) | FAPNSD2PREPDPP7PITRM1 | |
| SCHEMBL13101452 | 0.82 | FAP (0.53) | FAPNSD2PREPDPP7PITRM1 | |
| SCHEMBL23760562 | 0.82 | LMNA (0.64) | FAPMEN1KMT2APREPDPP9 | |
| SCHEMBL28834556 | 0.80 | HDAC3 (0.58) | FAPNSD2PREP | |
| SCHEMBL25752734 | 0.80 | FAP (1.00) | FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769443-A | Fibroblast activation protein inhibitor and use thereof | 3B制药有限公司 | 2024-03-26 | — | — | CN | disclosed |
| WO-2023002045-A1 | FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND USE THEREOF | 3B PHARMACEUTICALS GMBH (DE) | 2023-01-26 | — | — | WO | disclosed |
| EP-4122499-A1 | FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND USE THEREOF | 3B Pharmaceuticals GmbH (DE) | 2023-01-25 | — | — | EP | disclosed |