Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17898139 | 0.89 | PTPN11 (0.50) | PTPN11TSHRTDP1ALDH1A1KDM4E | |
| SCHEMBL15382499 | 0.89 | PTPN11 (0.53) | PTPN11TSHRTDP1ALDH1A1KDM4E | |
| SCHEMBL10412465 | 0.87 | PTPN11 (0.60) | PTPN11TSHRTDP1ALDH1A1KDM4E | |
| SCHEMBL16820808 | 0.84 | PTPN11 (0.46) | PTPN11TSHRTDP1ALDH1A1KDM4E | |
| SCHEMBL16840488 | 0.84 | PTPN11 (0.46) | PTPN11TSHRTDP1ALDH1A1KDM4E | |
| SCHEMBL16820845 | 0.84 | PTPN11 (0.46) | PTPN11TSHRTDP1ALDH1A1KDM4E | |
| SCHEMBL16840487 | 0.84 | PTPN11 (0.46) | PTPN11TSHRTDP1ALDH1A1KDM4E | |
| SCHEMBL16820634 | 0.83 | RARB (0.50) | PTPN11TSHRALDH1A1CA1CA2 | |
| SCHEMBL404435 | 0.83 | TSHR (0.62) | PTPN11TSHRTDP1ALDH1A1KDM4E | |
| SCHEMBL16820635 | 0.83 | RARB (0.50) | PTPN11TSHRALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981867-B1 | METHOD FOR PREPARING PROSTAGLANDIN DERIVATIVE | R-TECH UENO LTD (JP) | 2017-06-14 | — | — | EP | disclosed |
| US-9617256-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-9617256-B2 | Antibacterial agents | ACHAOGEN, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20170088549-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2017-03-30 | — | — | US | disclosed |
| EP-2170814-B1 | ANTIBACTERIAL AGENTS | ACHAOGEN INC (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2170814-B1 | ANTIBACTERIAL AGENTS | ACHAOGEN INC (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2735566-A1 | Method for preparing prostaglandin derivative | R-Tech Ueno, Ltd. (JP) | 2014-05-28 | — | — | EP | disclosed |
| EP-2662353-A2 | Antibacterial agents | Achaogen, Inc. (US) | 2013-11-13 | — | — | EP | disclosed |
| US-20130184476-A1 | PREPARATION OF LUBIPROSTONE | DR. REDDY'S LABORATORIES LTD. (IN) | 2013-07-18 | — | — | US | disclosed |
| US-8389748-B2 | Method for preparing prostaglandin derivative | SUCAMPO AG (CH) | 2013-03-05 | — | — | US | disclosed |
| EP-0507625-B1 | Method of producing alpha, beta unsaturated ketolactones | R TECH UENO LTD (JP) | 1996-08-28 | — | — | EP | disclosed |
| US-5468880-A | Method of producing α, β-unsaturated ketones | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1995-11-21 | — | — | US | disclosed |
| EP-0444844-B1 | New 15-dehydroxy-16-oxoprostaglandins | R TECH UENO LTD (JP) | 1995-01-18 | — | — | EP | disclosed |
| US-5229529-A | Method of producing α,β-unsaturated ketolactones | R-TECH UENO LTD. (JP) | 1993-07-20 | — | — | US | disclosed |
| US-5221763-A | 13,14-dihydro-15-keto-PGFs and salts | R-TECH UENO, LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| US-5221799-A | New 15-dehydroxy-16-oxoprostaglandins | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1993-06-22 | — | — | US | disclosed |
| EP-0507625-A1 | Method of producing alpha, beta unsaturated ketolactones | R-TECH UENO LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |
| US-5106869-A | Vasopressor activity without ephemeral vasorelaxation; no effect on trachea, intestine | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0289349-B1 | PROSTAGLANDINS OF THE F SERIES | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-01-29 | — | — | EP | disclosed |
| EP-0289349-A1 | Prostaglandins of the F series | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1988-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088549-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | PTPN11 3418/4885TSHR 4087/4885TDP1 3843/4885 |
| US-20130184476-A1 | PREPARATION OF LUBIPROSTONE | PTGIR, PTGIS, VASP | PTPN11 2317/4885TSHR 2143/4885TDP1 3703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.