Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.56 |
| ▸ | EHMT2 | Q96KQ7 | 8/20 | 0.55 |
| ▸ | EHMT1 | Q9H9B1 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24444648 | 0.87 | PDGFRB (0.59) | PDGFRBPDGFRAEHMT2EHMT1HRH3 | |
| SCHEMBL29616380 | 0.85 | PDGFRB (0.57) | PDGFRBPDGFRAEHMT2EHMT1ATM | |
| SCHEMBL29565672 | 0.77 | EHMT2 (0.63) | EHMT2EHMT1DNMT1 | |
| SCHEMBL5070073 | 0.76 | PDGFRB (0.59) | PDGFRBPDGFRAEHMT2HRH3DNMT1 | |
| SCHEMBL9377191 | 0.76 | PDGFRA (0.59) | PDGFRBPDGFRAEHMT2EHMT1 | |
| SCHEMBL29566096 | 0.75 | EHMT2 (0.70) | EHMT2EHMT1DNMT1 | |
| SCHEMBL4299023 | 0.74 | PDGFRB (1.00) | PDGFRBPDGFRASMN1; SMN2ALDH1A1 | |
| SCHEMBL30997309 | 0.73 | PDGFRB (0.68) | PDGFRBPDGFRASMN1; SMN2ATMLMNA | |
| Hydrochloric Acid SCHEMBL29357672 | 0.73 | PDGFRB (0.96) | PDGFRBPDGFRASMN1; SMN2ALDH1A1 | |
| SCHEMBL1591237 | 0.72 | AXL (0.80) | PDGFRAMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393363-B | 4-phenoxy quinoline and N-sulfonyl amidine compound and preparation method and application thereof | 威海海洋生物医药产业技术研究院有限公司 | 2022-12-20 | — | — | CN | disclosed |