Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24755685 | 1.00 | MCL1 (0.34) | MCL1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL24756664 | 0.81 | KMT2A (0.34) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL24755682 | 0.81 | MCL1 (0.38) | MCL1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL24756680 | 0.78 | RAB9A (0.46) | MCL1KDM4EHPGDL3MBTL1 | |
| SCHEMBL30136633 | 0.76 | ALDH1A1 (0.33) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL24756402 | 0.76 | ALDH1A1 (0.33) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL24756020 | 0.74 | — | — | |
| SCHEMBL24756298 | 0.70 | RAB9A (0.47) | MCL1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL24755688 | 0.69 | — | — | |
| SCHEMBL30136720 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334298-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | Scorpion Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022265993-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |