Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24756639 | 0.85 | RAB9A (0.34) | MCL1RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL24755685 | 0.81 | MCL1 (0.34) | MCL1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL30136728 | 0.81 | MCL1 (0.34) | MCL1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL30136602 | 0.80 | RAB9A (0.40) | RAB9ANPC1KMT2AMEN1PKM | |
| SCHEMBL24756665 | 0.80 | RAB9A (0.40) | RAB9ANPC1KMT2AMEN1PKM | |
| SCHEMBL24756679 | 0.77 | RAB9A (0.54) | MCL1RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL30136747 | 0.74 | ALDH1A1 (0.40) | MCL1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL30136720 | 0.69 | — | — | |
| SCHEMBL24755688 | 0.69 | — | — | |
| SCHEMBL30933146 | 0.68 | MCL1 (0.50) | MCL1RAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334298-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | Scorpion Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022265993-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| WO-2022265993-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |