Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22714073 | 1.00 | CYP11B1 (0.33) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22714072 | 1.00 | CYP11B1 (0.33) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4084097 | 0.90 | CYP11B1 (0.38) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22714066 | 0.84 | LMNA (0.36) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30137705 | 0.84 | LMNA (0.36) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22714067 | 0.84 | LMNA (0.36) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22714071 | 0.78 | SMN1; SMN2 (0.34) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22714069 | 0.78 | SMN1; SMN2 (0.34) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22728642 | 0.72 | MAPT (0.37) | KMT2ANPSR1HPGDKDM4EMAPT | |
| SCHEMBL22728641 | 0.72 | MAPT (0.37) | KMT2ANPSR1HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032668-B | Optically active 2,3-bisphosphinylpyrazine derivative, process for producing the same, transition metal complex, and process for producing organoboron compound | 日本化学工业株式会社 | 2022-10-14 | — | — | CN | disclosed |