Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22714073 | 1.00 | CYP11B1 (0.33) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30137702 | 1.00 | CYP11B1 (0.33) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4084097 | 0.90 | CYP11B1 (0.38) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22714066 | 0.84 | LMNA (0.36) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30137705 | 0.84 | LMNA (0.36) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22714067 | 0.84 | LMNA (0.36) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22714071 | 0.78 | SMN1; SMN2 (0.34) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22714069 | 0.78 | SMN1; SMN2 (0.34) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22728642 | 0.72 | MAPT (0.37) | KMT2ANPSR1HPGDKDM4EMAPT | |
| SCHEMBL22728641 | 0.72 | MAPT (0.37) | KMT2ANPSR1HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053265-B2 | Optically active substituted 2,3-bisphosphinoquinoxalines and processes for producing the same | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2021-07-06 | — | — | US | disclosed |
| US-20200377536-A1 | OPTICALLY ACTIVE 2,3-BISPHOSPHINOPYRAZINE DERIVATIVE, METHOD FOR PRODUCING SAME, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCING ORGANIC BORON COMPOUND | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2020-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200377536-A1 | OPTICALLY ACTIVE 2,3-BISPHOSPHINOPYRAZINE DERIVATIVE, METHOD FOR PRODUCING SAME, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCING ORGANIC BORON COMPOUND | ORC3, BMP2, TERT | CYP11B1 550/4885CYP11B2 256/4885SMN1; SMN2 4366/4885 |
| US-11053265-B2 | Optically active substituted 2,3-bisphosphinoquinoxalines and processes for producing the same | TBXA2R, TBC1D15, P2RY2 | CYP11B1 2904/4885CYP11B2 1748/4885SMN1; SMN2 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.