Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22714067 | 0.94 | LMNA (0.36) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22714066 | 0.94 | LMNA (0.36) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30137705 | 0.94 | LMNA (0.36) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30137702 | 0.90 | CYP11B1 (0.33) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22714073 | 0.90 | CYP11B1 (0.33) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22714072 | 0.90 | CYP11B1 (0.33) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5455643 | 0.80 | SMN1; SMN2 (0.42) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22714069 | 0.77 | SMN1; SMN2 (0.34) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22714071 | 0.77 | SMN1; SMN2 (0.34) | CYP11B1CYP11B2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4280741 | 0.74 | TSHR (0.37) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608709-B2 | 2, 3-bis(dialkylphosphino)pyrazine derivative, process of producing the same, and metal complex having the same as ligand | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2009-10-27 | — | — | US | claimed |
| US-8076480-B2 | Process of preparing optically active allyl compound | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2011-12-13 | — | — | US | disclosed |
| US-8076480-B2 | Process of preparing optically active allyl compound | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2011-12-13 | — | — | US | disclosed |
| US-8076480-B2 | Process of preparing optically active allyl compound | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2011-12-13 | — | — | US | disclosed |
| US-7649117-B2 | Process of preparing optically active β-hydroxycarboxylic acid derivative | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2010-01-19 | — | — | US | disclosed |
| US-7608709-B2 | 2, 3-bis(dialkylphosphino)pyrazine derivative, process of producing the same, and metal complex having the same as ligand | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2009-10-27 | — | — | US | disclosed |
| US-20090030231-A1 | PROCESS OF PREPARING OPTICALLY ACTIVE B-HYDROXYCARBOXYLIC ACID DERIVATIVE | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2009-01-29 | — | — | US | disclosed |
| US-20090030231-A1 | PROCESS OF PREPARING OPTICALLY ACTIVE B-HYDROXYCARBOXYLIC ACID DERIVATIVE | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2009-01-29 | — | — | US | disclosed |
| US-20090030200-A1 | PROCESS OF PREPARING OPTICALLY ACTIVE ALLYL COMPOUND | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2009-01-29 | — | — | US | disclosed |
| US-20090030200-A1 | PROCESS OF PREPARING OPTICALLY ACTIVE ALLYL COMPOUND | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2009-01-29 | — | — | US | disclosed |
| US-20090030200-A1 | PROCESS OF PREPARING OPTICALLY ACTIVE ALLYL COMPOUND | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030200-A1 | PROCESS OF PREPARING OPTICALLY ACTIVE ALLYL COMPOUND | DHPS, ITPA, PDXK | CYP11B1 1120/4885CYP11B2 936/4885SMN1; SMN2 4206/4885 |
| US-20090030231-A1 | PROCESS OF PREPARING OPTICALLY ACTIVE B-HYDROXYCARBOXYLIC ACID DERIVATIVE | KMO, DHPS, KHK | CYP11B1 834/4885CYP11B2 528/4885SMN1; SMN2 4828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.