Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.38 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26631562 | 1.00 | PTGES (0.40) | PTGESKDM4EMAPTALDH1A1DHODH | |
| SCHEMBL26631533 | 0.83 | DHODH (0.54) | KDM4EDHODHPKN1PKN2 | |
| SCHEMBL23925332 | 0.82 | RNASEH1 (0.50) | PTGESKDM4EMAPTALDH1A1DHODH | |
| SCHEMBL30242145 | 0.81 | DHODH (0.44) | MAPTDHODHPKN1PKN2MMP2 | |
| SCHEMBL20482842 | 0.81 | DHODH (0.44) | MAPTDHODHPKN1PKN2MMP2 | |
| SCHEMBL15808917 | 0.80 | PRMT5 (0.41) | KDM4EMAPTALDH1A1PRMT5WDR77 | |
| SCHEMBL29025404 | 0.79 | MAPT (0.41) | PTGESKDM4EMAPTALDH1A1MMP2 | |
| SCHEMBL6841804 | 0.78 | PKN1 (0.57) | KDM4EMAPTALDH1A1PKN1PKN2 | |
| SCHEMBL30138975 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1DHODHPKN1PKN2 | |
| SCHEMBL26631538 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1DHODHPKN1PKN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115485266-A | Benzimidazole derivatives | 豪夫迈·罗氏有限公司 | 2022-12-16 | — | — | CN | disclosed |